Pharmacy

Location:  University Park 

Salary:  £29,762 to £38,474 per annum (pro rata if applicable) depending on skills and experience (minimum £33348 with relevant PhD). 

Closing Date:  Tuesday 20 June 2023 

Reference:  SCI245523

We are seeking a Research Associate/Fellow to join a project funded by Innovate UK at the University of Nottingham, working in partnership with TherageniX Ltd. The project aim is to develop an advanced therapeutic using genetic augmentation for enhanced bone repair using clinical samples. The role holder will be involved in the design, build and testing of pivotal gene delivery, cell differentiation and hydrogel scaffold-based systems. The successful candidate will join highly motivated and multidisciplinary research teams across the School of Pharmacy; and in collaboration with spin-out TherageniX and East midlands trauma centre and the BRC Musculoskeletal theme of the Nottingham NIHR.

The aim of this post will be to develop a gene delivery-focused augmentation strategy for orthopaedic regenerative medicine. We have recently designed and implemented an efficient gene delivery system and have applied this to induce bone differentiation in the context of an advanced hydrogel-based systems for tissue engineering and in animal models. Here, we aim to build on these successes by further enhancing the methodology to apply to clinical samples and medical devises as the next stage of translation. 

Candidates should have a PhD submitted or awarded in a discipline relevant to cell biology and/or tissue engineering. Past experience of bone cell culture, hydrogel systems and cell differentiation assays and preferably also gene delivery systems is essential. A knowledge of advanced analysis of differentiation (Immunolabelling, gene expression analyses) would be desirable. The candidate will be required to undertake research and day to day management of design, construct and test aspects of this research project, requiring a high degree of competence in the cell and tissue engineering biology research area. An aptitude for critical thinking and a flexible approach to collaborative research is vital.

This full-time post (36.25 hours per week) will be offered on a fixed-term contract until 30th September 2025. Job share arrangements may be considered.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues visit www.nottingham.ac.uk/jobs/applyingfromoverseas/index2.aspx

We pride ourselves on the collegial and supportive culture created by our staff. We are dedicated to creating an environment which enables both our staff to thrive and achieve their potential. Our commitment to Equality and Diversity has been recognised in the awarding of an Athena SWAN Silver Award.

Informal enquiries can be addressed to Dr James Dixon (james.dixon@nottingham.ac.uk) . Please note that applications sent directly to these email addresses will not be accepted.

Further details:

• Job Description/Role Profile

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Our University is a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, see our Moving to Nottingham pages.

Please note that applicants for this post will be considered on an equal basis, subject to the relevant permission to work in the UK as defined by the requirements set out by UK Visas & Immigration.  Please visit: https://www.gov.uk/government/organisations/uk-visas-and-immigration for more information.

For successful international applicants, we provide financial support for your visa and the immigration health surcharge, plus an interest-free loan to help cover the cost of immigration-related expenses for any dependents accompanying you to the UK. For more information please see the our webpage on Financial support for visas and the immigration health surcharge.