Outline

Drug resistance is an increasing health and economic concern with the emergence of diseases that respond poorly to standard treatment regimes. There are numerous ways by which drug resistance and drug deactivation can arise. The development of drugs that overcome these pathways is a key challenge today. This studentship will examine how highly strained alicyclic hydrocarbon systems, can be used to overcome and probe mechanisms of drug resistance in cancer therapeutics and antibiotics.

The studentship will provide expert training in synthetic chemistry, reaction development and medicinal chemistry, through the Tredwell and Fallis Groups in the School of Chemistry. Students will also develop the skills to perform biological assays and broader training in medical imaging and materials science.

The make-up of the supervisory team and collaborators allows the applicant to be participate in research across the interface of chemistry, biology and materials. The interdisciplinary nature of the research will provide the applicant with a comprehensive practical skillset and broad theoretical background ideally positioning them for careers in industrial or academic sectors.

Supervisory team

Dr Matthew Tredwell and Dr Ian Fallis.

What is funded

The studentship includes fees, stipend and RTSG. The stipend and fees are at the UKRI rate (for 2020/21 is £15,285; £4,407 respectively).

Students must meet the eligibility criteria, outlined in the terms and conditions on the UKRI website.

International applicants should note that they may be required to cover the difference between Home and International fees each year.

Duration

This is a 3.5 year EPSRC DTP studentship with a start date of 1st October 2021.

Eligibility

Candidates should hold or expect to gain a first class degree or a good 2.1 and/or a Master’s level qualification (or their equivalent) in chemistry with project experience in synthetic organic and inorganic chemistry.  

Applicants whose first language is not English will be required to demonstrate proficiency in the English language (IELTS 6.5 or equivalent)

How to Apply

Please complete an online application stating this project title: https://www.cardiff.ac.uk/study/postgraduate/research/programmes/programme/chemistry

Please include in your application a CV and personal statement confirming your suitability for this post.

The deadline for this post is Friday 15th January. We will not be contacting applicants before this date.

Interviews will be held by online (via zoom) the week commencing Monday 1st February.

As part of the interview applicants will be required to give a five minute presentation on their chemistry experience to date.