23/09/2020
The Human Resources Strategy for Researchers

PhD thesis in Pharmaceutical Sciences

Dieses Jobangebot ist nicht mehr aktuell


  • ORGANISATION/EINRICHTUNG
    Université Catholique de Louvain (UCL)
  • FORSCHUNGSBEREICH
    Pharmacological sciencesPharmacy
  • KARRIERESTUFE
    First Stage Researcher (R1)
  • BEWERBUNGSFRIST
    23/10/2020 21:00 - Europe/Brussels
  • STANDORT
    Belgium › Brussels
  • KONTAKTTYP
    Temporary
  • JOB STATUS
    Full-time
  • STUNDEN PRO WOCHE
    38
  • ANGEBOT BEGINN
    26/10/2020

OFFER DESCRIPTION

Pulmonary arterial hypertension (PAH) is a severe and incurable cardiopulmonary condition characterized by a marked and sustained increase in mean pulmonary artery pressure that ultimately leads to right ventricular failure and death. Since the diseased arterioles are located in the immediate vicinity of respiratory bronchioles and alveoli, inhalation of aerosols could provide a more efficacious, safer and more convenient mode of delivery of vasodilator drugs in PAH than injection or oral delivery. This could especially be the case if the vasodilator is delivered to the lungs as a sustained-release formulation. The goal of this project will be to prepare a long-acting vasodilator nanomedicine for inhalation in PAH. The project will include the preparation of the sustained-release formulation of a selected vasodilator compound and its physicochemical and biological characterization in vitro. It will also involve a contribution to the assessment of its lung pharmacokinetics in healthy rats and to the evaluation of its therapeutic efficacy in rat models of pulmonary hypertension.

This competitive 42-month project is funded the Fonds National de la Recherche Scientifique (www.fnrs.be). The project will be performed in collaboration with Prof. Raphael Frédérick (LDRI, UCLouvain) and Prof. Frédéric Perros of the University of South Paris. You will receive a 12 month doctoral fellowship with a net allocation of 1980€ per month. The fellowship will start October 15th 2020 the earliest and will be renewable thrice for a total of 42 months.

Mehr Information

Benefits

Free transportation pass

Eligibility criteria

Master in Pharmaceutical Sciences required.

Selection process

If you are interested, please send a letter of application along with your curriculum vitae, your bachelor and master degrees notes transcripts and the names and contact information of 2 references, by email to:

Prof. Rita Vanbever, rita.vanbever@uclouvain.be

Advanced Drug Delivery & Biomaterials - LDRI - UCLouvain - Brussels - Belgium

Web site for additional job details

Erforderliche Forschungserfahrung

  • FORSCHUNGSBEREICH
    Pharmacological sciencesPharmacy
  • JAHRE DER FORSCHUNGSERFAHRUNG
    1 - 4

Anforderungen für das Jobangebot

  • ERFORDERLICHES BILDUNGSNIVEAU
    Pharmacological sciences: Master Degree or equivalent
  • ERFORDERLICHE SPRACHEN
    OTHER: Basic

Kenntnisse/Qualifikationen

  • You have recently obtained a master degree in pharmaceutical sciences.
  • Laboratory experience in organic chemistry, chromatography, mass spectrometry, 1H NMR and cell culture is a plus.
  • You possess good communicational skills in English.

Besondere Anforderungen

None

Arbeitsort
1 position(s) available at
UCLouvain/LDRI
Belgium
Brussels
1200
73, avenue Emmanuel Mounier

EURAXESS Angebots-ID: 561118

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